Here are the 49 US AI startups that have raised $100M or more in 2025
The Rise of US AI Startups: A Year of Record-Breaking Fundraising
As we approach the end of 2025, the US AI startup scene has witnessed a remarkable year of growth, with a record number of companies raising significant funding rounds. According to our count, there are 49 US AI startups that have raised $100 million or more in funding this year, surpassing the previous year's numbers. This trend is a testament to the increasing interest and investment in AI technologies, which are transforming industries and revolutionizing the way we live and work.
Notable Funding Rounds in 2025
One of the most notable funding rounds of the year was raised by Anysphere, a maker of viral vibe-coding platform Cursor, which raised $2.3 billion in a funding round that valued the company at $29.3 billion. This round was announced in November and is the company's second funding round this year. Another notable round was raised by Parallel, which builds web infrastructure for AI agents, which raised a $100 million Series A round co-led by Index Ventures and Kleiner Perkins.
In October, Fireworks AI, a platform that allows users to build AI applications using open source models, raised a $250 million Series C round that valued the company at $4 billion. Enterprise AI startup Uniphore is valued at $2.5 billion after a $260 million Series F round that was announced on October 22. Sesame, a voice AI company, raised a $250 million Series B round co-led by Sequoia and Spark Capital.
AI Infrastructure and Research
AI infrastructure and research have been a significant focus area for many startups this year. Cerebras Systems, an AI infrastructure company, raised a sizable $1.1 billion Series G round that valued the company at $8.1 billion. The round was announced on September 30 and was co-led by Fidelity and Atreides Management. Modular announced a $250 million funding round on September 24, which was led by US Innovative Technology Fund with participation from GV, Greylock, and General Catalyst, among others.
Healthcare and AI
Healthcare and AI have been a significant area of focus for many startups this year. EliseAI, a healthcare and housing automation platform, raised $250 million in a Series E round that valued the startup at $2.2 billion. The round was led by Andreessen Horowitz. Decart, an AI research lab, raised $100 million at a $3.1 billion valuation. The round included Sequoia Capital, Benchmark, and Zeev Ventures, among others.
Generative Media and AI
Generative media and AI have been a significant area of focus for many startups this year. Fal, a generative media platform, raised a $125 million Series C round led by Meritech Capital Partners. The company announced the round, which values Fal at $1.5 billion, on July 31. Salesforce Ventures, Shopify Ventures, Google AI Futures Fund, and others joined the round.
Conclusion
The US AI startup scene has witnessed a remarkable year of growth, with a record number of companies raising significant funding rounds. This trend is a testament to the increasing interest and investment in AI technologies, which are transforming industries and revolutionizing the way we live and work. As we look to the future, it will be exciting to see how these startups continue to innovate and push the boundaries of what is possible with AI.
Forward-Looking Thoughts
As we move forward, it will be essential to continue investing in AI research and development to ensure that these technologies are developed and deployed responsibly. It will also be crucial to address the challenges and risks associated with AI, such as job displacement and bias. By working together, we can ensure that AI is developed and used in a way that benefits society as a whole.
Key Takeaways
- 49 US AI startups have raised $100 million or more in funding this year
- Anysphere raised $2.3 billion in a funding round that valued the company at $29.3 billion
- Parallel raised a $100 million Series A round co-led by Index Ventures and Kleiner Perkins
- Fireworks AI raised a $250 million Series C round that valued the company at $4 billion
- Cerebras Systems raised a $1.1 billion Series G round that valued the company at $8.1 billion
- EliseAI raised $250 million in a Series E round that valued the startup at $2.2 billion
- Decart raised $100 million at a $3.1 billion valuation
Implications
The increasing investment in AI startups has significant implications for the future of work and the economy. As AI technologies continue to transform industries, it will be essential to address the challenges and risks associated with AI, such as job displacement and bias. By working together, we can ensure that AI is developed and used in a way that benefits society as a whole.
